Dr. Laurence Gluch

Breast and Reconstructive Surgeon, Thyroid Surgeon

Breast and Reconstructive Surgeon, Thyroid Surgeon.

Dr Laurence Gluch is a specialist breast and thyroid surgeon.  He graduated from the University of the Witwatersrand in 1985. He completed his advanced surgical training at Royal North Shore Hospital becoming a Fellow of the Royal Australasian College of Surgeons.

After receiving his surgical fellowship he undertook research in Magnetic Resonance at the Institute for Magnetic Resonance Research in Sydney and in 2003 was awarded a Ph.D. by the University of Sydney for his thesis on the application of Magnetic Resonance Spectroscopy and Imaging in the diagnosis of Breast Cancer. He undertook a visiting fellowship with Dr. Ferenc Jolesz, pioneer of interventional magnetic resonance surgery, at the Brigham and Womens’ Hospital and Harvard Medical School in Boston.

Dr Gluch now works in both the public and private hospital systems offering patients compassionate care in general surgery with a particular focus on breast and thyroid disorders. He utilises state of the art techniques aiming always to offer patients the very best cosmetic results while having an excellent understanding of what is required to treat the cancer. Where appropriate he is able to offer women immediate breast reconstruction.

As an endocrine surgeon he specialises in the surgical management of benign and malignant thyroid and parathyroid gland disorders.

Dr Gluch holds memberships in the Breast and Endocrine sections of the Royal Australasian College of Surgeons.  He is also a member of the International Surgical Society and the Australasian Society for Breast Diseases. He actively participates in multidisciplinary team meetings at The Strathfield Breast Centre

He operates at Concord Hospital and the Strathfield Private Hospital and holds an appointment as Clinical Lecturer in Surgery at the University of Sydney.

Dr Gluch has a strong commitment to developing new knowledge and understanding of surgical problems and serves as an Editor for the Open Access Journal Frontiers in Oncology.

From a relatively diverse range of interests during his training years Dr Gluch has necessarily focused his research to improving breast cancer diagnosis and treatment.  Below is a list of his publications showing this broad scope of work.  Open Access publications can be downloaded by clicking on the link.

 

  1. Gluch L, Poels D. Lost for Words – Bilateral Vocal Cord Paresis following Renal Dialysis of a Thyroidectomy Patient Eur J Clin Med 2023: https://www.ej-clinicmed.org/index.php/clinicmed/article/view/304
  2. Girithar HN, Staats-Pries A, Ahn SB, Guillemin GJ, Gluch L and Heng B. Involvement of the kynurenine pathway in breast cancer: updates on clinical research and trials British Journal of Cancer 2023 doi: https://www.nature.com/articles/s41416-023-02245-7
  3. Wu SZ, Al-Eryani G, Roden D, Junankar S, Harvey K, Andersson A, Thennavan A, Wang C, Torpy J, Bartonicek N, Wang T, Larsson L, Kaczorowski D, Weisenfeld NI, Uytingco CR, Chew JG, Bent ZW, Chan CL, Gnanasambandapillai V, Dutertre CA, Gluch L, Hui MN, Beith J, Parker A, Robbins E, Segara D, Mak C, Cooper C, Chan B, Warrier S, Ginhoux F, Millar E, Powell J, Williams SR, Liu XS, O’Toole S, Lim E, Lundeburg J, Perou CM, Swarbrick A. A single-cell and spatially resolved atlas of human breast cancers Nature Genetics2021, 53, 1334-1347
  4. Heng B, Bilgin AA, Lovejoy DB, Tan VX, Milioli HH, Gluch L, Busamante S, Moscato P, Lim CK and Guillemin GJ. Differential kynurenine pathway metabolism in highly-metastatic aggressive breast cancer subtypes: beyond IDO1-induced immunosuppression Breast Cancer Research 2020, 22:113 doi: https://doi.org/10.1186/s13058-020-01351-1
  5. Roden D.L, Baker L.A, Elsworth B, Wu S.Z, Harvey K, Chan C-L, Deng N, Segara D, Parker A, Mak C, Beith J, Chan B, Carmalt H, Gluch L, O’Toole S, Hui M, Robbins E, Warrier S, Lim E, Cazet A, Nair R, Swarbrick A. Single cell transcriptomics reveals marked heterogeneity for intrinsic molecular subtype and cellular function in breast cancer models and clinical tissue The EMBO Journal Jun 2020, doi: https://doi.org/10.1101/2020.06.04.135327
  6. Wu SZ, Roden D, Wang C, Holliday H, Harvey K, Cazet A, Murphy K, Pereira B, Al-Eryani G, Bartonicek N, Hou R, Torpy J, Junankar S, Chan CL, Lam CE, Hui M, Gluch L, Beith J, Parker A, Robbins E, Segara D, Mak C, Cooper C, Warrier S, Forrest A, Powell P, O’Toole S, Cox T, Timpson P, Lim E, Liu XS, Swarbrick A. Stromal cell diversity associated with immune evasion in human triple negative breast cancer The EMBO JournalAugust 2020 doi: https://doi.org/10.15252/embj.2019104063
  7. Gluch L, Sahyoun M, Mander Jones T. The Brilliance of Contrast Enhanced Spectral Mammography J Gen Surg 2020, 3(3) 025.
  8. Gluch L, Gluch N. A surgeon, a rabbi and a lawyer walk in to an OR… Absorbable haemostatic agents and the dangers of product evolution – clinical, religious and legal implications AMJ 2018, 11(1) 18-24.
  9. Beckers RK, Selinger C, Vilain R, Madore J, Wilmott J, Harvey K, Holliday A, Cooper C, Robbins E, Gillett D, Kennedy CW, Gluch L, Carmalt H, Mak C, Warrier S, Gee HE, Chan C, McLean A, Walker E, McNeil CM, Beith CM, Swarbrick A, Scolyer RA, O’Toole SA. PD-L1 expression in triple-negative breast cancer is associated with tumor-infiltrating lymphocytes and improved outcome in TNBC Histopathology2016, 69(1) 25-34.
  10. Heng B, Lim CK, Lovejoy DB, Bessede A, Gluch L, Guillemin GJ. Understanding the role of the kynurenine pathway in human breast cancer immunobiology Oncotarget 2015, 7(6) 6506-6520.
  11. Norddin N, Power C, Watson G, Cowin G, Kurniawan N, Gluch L, Bourne R. Microscopic diffusion properties of fixed breast tissue: Preliminary findings MRM2015, 74(6) 1733-1739.
  12. Stanwell P, Gluch L. Lipid and Metabolite Deregulation in BRCA1 and BRCA2 Genetic Mutations (Letter)Radiology2015, 277(2) 614-615.
  13. Loh SF, Cooper C, Selinger CI, Barnes E, Chan C, Carmalt H, West R, Gluch L, Beith JM, Caldon E, O’Toole S. Cell cycle marker expression in benign and malignant intraductal papillary lesions of the breast Journal of Clinical Pathology2015, 68(3): 187-91.
  14. Lea V, Gluch L, Kennedy CW, Carmalt HL, Gillett DJ. Tubular Carcinoma of the Breast: Axillary involvement and prognostic factors ANZJSurg2015, 85(6) 448-51.
  15. Uren, R.F, Howman-Giles, R, Chung, D.K.V, Spillane, A.J, Noushi, F, Gillett, D, Gluch, L, Mak, C, West, R, Briody, J, Carmalt, H. SPECT/CT scans allow precise anatomical location of sentinel lymph nodes in breast cancer and redefine lymphatic drainage from the breast to the axilla The Breast2012, 21: 480-486.
  16. Perera N, Gluch L, Crawford BA. Misleading parathyroid sestamibi scan in lithium users Internal Medicine Journal2009; 39: 556–559.
  17. Elder EE, Kennedy CW, Gluch L, Carmalt HL, Janu NC, Joseph MG, Donellan MJ, Molland JG, Gillett DJ. Patterns Of Breast Cancer Relapse EJSO 2006; 32: 922-927.
  18. Gluch L. Magnetic Resonance in Surgical Oncology: II. A Literature Review ANZ J. Surg.2005;75: 464–470.
  19. Gluch L. Magnetic Resonance in Surgical Oncology: I. On the Origin of the Spectrum ANZ J. Surg.2005; 75: 459–463.
  20. Stanwell P, Gluch L, Clark D, Tomanek B, Baker L, Giuffré B.M, Lean C.L, Malycha P, Mountford C.E.  Specificity of Choline Metabolites for in-vivo Diagnosis of Breast Cancer using 1H MRS at 1.5T. Eur Radiol2005 15:1037–1043.
  21. Peters MJ, Morgan L, Gluch L. Smoking cessation and elective surgery: the cleanest cut. MJA2004 180(5) 317-318.
  22. Gluch L and Walker DG. Interventional Magnetic Resonance: The Future of Surgery. ANZ J. Surg. 2002; 72: 426–436.
  23. Mountford CE, Somorjai RL, Malycha P, Gluch L, Lean C, Russell P, Barraclough B, Gillett D, Himmelreich U, Dolenko B, Nikulin AE, Smith IC; Diagnosis and prognosis of breast cancer by magnetic resonance spectroscopy of fine-needle aspirates analysed using a statistical classification strategy BJS 2001; 88(9): 1234-40.
  24. Gluch L, Smith RC, Bambach CP; Brown AR. Comparison of Outcomes following Transhiatal or Ivor Lewis Oesophagectomy for Oesophageal Carcinoma World Journal Of Surgery. 1999; 23(3):271-5; Discussion 275-6.
  25. Evans JP, Chan C, Gluch L, Fielding IR, Eckstein R. Inflammatory Pseudotumour Secondary to Actinomyces Australian & New Zealand Journal of Surgery. 1999; 69(6):467-9.
  26. Gluch L, Fenton-Lee D, Morris DL, Stewart MG. Advances in the use of Suction Curette for the management of Hydatid Cysts BJS1995; 82: 1697.
  27. Gluch L, Khouri JM. Pseudohyperkalaemia after Splenectomy: Pitfall for the Unwary MJA1994; 161:509.